Top 5 VC Deals of the Week in AI (11/28/25)

By
Christopher Robbins
-
92

This week we continue our series on the top 5 VC-funded deals in AI.

This week’s venture capital funding remained brisk, with five transactions in excess of the $100 million threshold.

The top reported deal, per FinSMEs, came from San Francisco-based multimodal artificial general intelligence developer Luma AI, which raised $900 million in a Series C. Luma AI will use the funds to “extend its position in entertainment and advertising into simulation, design, and robotics,” according to its announcement. Our second announcement is from Palo Alto, Calif.-based Genspark, which raised a $275 million Series B to “expand operations and its business reach,” according to its announcement. The top five also included companies in the life sciences, superintelligence and life sciences sectors.

Smaller funding raises that did not quite make our top 5 this week included announcements from the defense, cybersecurity and financial spaces.

Below, we highlight the top five venture capital deals, ranked from the highest to the lowest funding amounts, showcasing the companies at the forefront of the AI revolution…

Top 5 Venture Capital Deals from Nov. 20 – Nov. 26

1. Luma AI

  • Location: San Francisco, CA

  • Description: Luma AI is building a multimodal artificial general intelligence (AGI) platform that blends visual, textual, and interactive capabilities to support general-purpose AI applications.

  • Funding Amount: $900 million

  • Funding Round: Series C

2. Genspark

  • Location: Palo Alto, CA

  • Description: Genspark is an agentic AI company focused on autonomous software agents that can reason, plan, and act on behalf of users, accelerating enterprise workflows and digital transformation.

  • Funding Amount: $275 million

  • Funding Round: Series B

  • Valuation: $1.25 billion

3. Harmonic

  • Location: Palo Alto, CA

  • Description: Harmonic is an AI lab developing Mathematical Superintelligence (MSI), with a mission to advance next-generation reasoning and problem-solving capabilities in AI systems.

  • Funding Amount: $120 million

  • Funding Round: Series C

  • Valuation: $1.45 billion

4. Profluent

  • Location: Emeryville, CA

  • Description: Profluent is pioneering the application of frontier AI in protein design, using generative technologies to develop novel proteins with therapeutic potential.

  • Funding Amount: $106 million

  • Funding Round: Undisclosed

5. RapidSOS

  • Location: New York, NY

  • Description: RapidSOS provides a public safety AI platform that connects real-time data from connected devices to emergency responders, improving crisis response and saving lives.

  • Funding Amount: $100 million

  • Funding Round: Undisclosed

Make sure to check out our Top 5 VC Deals of the Week in AI right here!

Written & Researched by DWN Staff
VC Deals Synopsized by ChatGPT
Research Source: FinSMEs

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